Prometrium is a progesterone supplement made from plant sources and processed to be chemically identical to the progesterone produced by the human body. It is used to treat menstrual irregularities, support menopause therapy, and maintain hormonal balance during fertility treatments. Prometrium capsules come in 100 mg and 200 mg strengths and are taken orally, usually once daily at bedtime.

Unlike synthetic progestins, Prometrium uses micronized progesterone, which is more easily absorbed by the body. This makes it a preferred option for women seeking a natural alternative for hormone therapy or fertility support.